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Updated: Jun 12, 2025

Methods for the Modulation and Analysis of NF-κB-dependent Adult Neurogenesis
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抑制IGFBP7可通过调节ERK1/2通路来缓解LPS诱导的核脉细胞损伤

Jun Gao1, Chunsheng Gao1, Xiaowei Wang1

  • 1Department of Orthopaedics, The Third People's Hospital of Hubei Province, Wuhan, 430033 China.

Cytotechnology
|June 9, 2025
PubMed
概括

椎间盘退化 (IDD) 涉及细胞核脉 (NP) 细胞. 这项研究发现,抑制胰岛素样生长因子结合蛋白7 (IGFBP7) 通过ERK1/2通路减少NP细胞亡和炎症,这表明IGFBP7是IDD的治疗标.

关键词:
通过ERK1/2路径.IGFBP7 IGFBP7 IGFBP7 IGFBP7 IGFBP7 IGFBP7 IGFBP7 IGFBP7椎间盘退化 椎间盘退化它的核心是脉的.

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