在艾滋病毒感染的老年人中遵守骨密度查建议
Madison Martz1, Nazar Akhverdyan1, Melissa P Wilson2
1School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
AIDS research and human retroviruses
|June 9, 2025
概括
通过双能X射线吸收计 (DXA) 查骨矿物质密度 (BMD) 建议对艾滋病毒感染的老年人进行查,但查率仍然很低. 这项研究发现,许多高风险的艾滋病毒感染者没有得到充分的查,这凸显了改善骨健康监测的必要性.
科学领域:
- 骨健康 骨健康 骨健康
- 艾滋病毒 医学 艾滋病毒 医学
- 老年病的医生 老年病的医生
背景情况:
- 艾滋病毒指南建议在绝经后的女性和50岁及以上的男性使用双能X射线吸收计 (DXA) 进行骨矿物密度 (BMD) 查.
- 这些关键查建议的采用率显著低.
- 艾滋病毒感染的老年人患骨质疏松症和骨折的风险增加.
研究的目的:
- 确定65岁及以上的艾滋病毒感染者 (PWH) 骨矿物密度 (BMD) DXA查完成率.
- 评估该人口中低BMD,骨质疏松症和骨质疏松症的患病率.
- 评估遵守当前针对骨折风险的艾滋病毒查指南.
主要方法:
- 电子健康记录的回顾性横截面分析.
- 纳入标准:65岁或以上的艾滋病毒感染者 (PWH) 接受常规护理.
- 收集了300个PWH (243名男性,57名女性) 的DXA订单完成和BMD结果的数据.
主要成果:
- 只有48%的符合条件的PWH订购了DXA扫描;85%的订单有可用的结果.
- 在接受查的人群中,骨质疏松症被诊断为42%的女性和20%的男性.
- 骨质疏松症的患病率在女性中为45%,在男性中为53%,女性13%和男性27%的BMD正常.
结论:
- 尽管目前的指导方针,高骨折风险的艾滋病毒感染者 (PWH) 的老年人缺乏低骨矿物质密度 (BMD) 的查.
- 显著需要改善骨折风险评估和查协议,以此脆弱的患者群体.
- 及时的DXA查对于管理艾滋病毒感染老年人的骨健康至关重要.
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