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Updated: Jan 18, 2026

A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.
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A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.

Published on: February 14, 2021

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在椎间盘退化中探索炎症性细胞因子的上游和下游因果关系:双向,双样本的门德尔随机化研究

Pan Huang1, Yi He1, Na Zhi1

  • 1Acupunctrue and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, 610000, China.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
|June 9, 2025
PubMed
概括

这项研究揭示了炎症性细胞因子与椎间盘退化有因果关系. 关键的上游调节剂包括cystatin D和IL-15受体亚单元alpha,而IL-13和IL-2可能会提供下游的保护作用.

关键词:
炎症性细胞因子是炎症性细胞因子.椎间盘退化 椎间盘退化门德尔的随机化

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