吸烟状态与非酒精性脂肪肝疾病之间的关联
Hyun Joe1, Jung-Eun Oh2, Yong-Jin Cho2
1Department of Family Medicine, College of Medicine, Soonchunhyang University College of Medicine, Soonchunhyang University Seoul Hospital, Seoul, Korea.
吸烟显著增加了非酒精性脂肪性肝病 (NAFLD) 的风险. 然而,戒烟超过10年的时间与发展NAFLD的可能性降低有关.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 烟草吸烟与非酒精性脂肪性肝病 (NAFLD) 之间的联系受到争议.
- 新出现的证据表明,吸烟是NAFLD发展的关键风险因素.
研究的目的:
- 在韩国男性中调查吸烟状态和NAFLD之间的关联.
- 探索戒烟对NAFLD患病率的影响.
主要方法:
- 一项对12241名接受健康检查的成年男性进行横截面研究.
- 通过腹部超声波进行NAFLD诊断.
- 使用后勤回归分析吸烟状态,包装年和戒烟持续时间.
主要成果:
- 在前吸烟者中,NAFLD的调整几率比率 (aOR) 为1.190.
- 当前吸烟者在较高包装年 (aORs 1.289和1.235) 时显示NAFLD风险增加.
- 随着戒烟持续时间的延长,NAFLD的患病率下降 (aOR分别为0.748和0.750>10年和>20年).
结论:
- 吸烟与发展NAFLD的更高几率有显著的关联.
- 戒烟超过10年的时间与NAFLD的几率降低有关.
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