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[患有急性淋巴细胞白血病的儿科患者的欧米茄-3多不和脂肪酸]

Sharon Berenice Morales-Montes¹, Salvador Atilano-Miguel¹, María de Lourdes Barbosa-Cortés¹

¹Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Pediatría "Dr. Silvestre Frenk Freund", Unidad de Investigación Médica en Nutrición. Ciudad México, México.

Revista medica del Instituto Mexicano del Seguro Social

|June 9, 2025

概括

欧米茄-3脂肪酸在儿童白血病治疗中表现有前途,通过保持瘦体质量和管理副作用. 需要进一步的研究来证实对接受癌症治疗的儿童有这些益处.

科学领域:

营养科学营养科学
在瘤学瘤学.
儿科血液学儿科血液学

背景情况:

欧米茄-3长链多不和脂肪酸 (LC-PUFA) 越来越多地被认为具有健康益处.
研究表明LC-PUFA可以降低代谢风险,甘油三和炎症,并保持瘦体质量.
在成人癌症患者中,LC-PUFA具有作为辅助疗法的潜力,增强化疗效率和患者存活率.

研究的目的:

审查目前关于在急性淋巴细胞白血病 (ALL) 的儿科患者中补充omega-3脂肪酸的证据.
突出LC-PUFA对儿童白血病营养状况和治疗相关毒性的影响.

主要方法:

对涉及儿童ALL患者omega-3脂肪酸补充剂的干预研究的综述.
分析报告的与瘦身量,脂质配置文件,心血管风险和药物毒性相关的结果.

主要成果:

对于儿童白血病中使用LC-PUFA补充剂的证据有限.
潜在的益处包括保持瘦身量和控制脂质不良症.
在治疗期间,LC-PUFA可能会减轻甲醇酸诱导的肝毒性.

结论:

欧米茄-3脂肪酸可能在儿科ALL治疗中提供支持性益处.
进一步的研究至关重要,以确定在这个人群中最佳的使用和有效性.
营养干预是对瘤血液学治疗结果至关重要的,可修改的因素.

关键词:

食补充剂食补充剂脂肪酸,欧米茄-3 脂肪酸,欧米茄-3 脂肪酸心脏病的危险因素心脏病的危险因素瘦身身体质量瘦身身体质量前体细胞淋巴细胞白血病-淋巴瘤.

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