患有COVID-19的个体肝功能障碍及其对怀孕结果的影响
Minqin Yan1, Qiaoqiao Zhan, Xiumei Wu
1Department of Gynecology and Obstetrics, Anhui Women and Children's Medical Center, Hefei Maternal and Child Health Hospital, Hefei, P. R. China.
感染COVID-19的孕妇面临肝功能异常的高风险,母亲的晚年,妊娠年龄和BMI增加了这种风险. 这些肝脏问题可能导致不良的妊娠结果.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 肝病学 肝病学是一种肝病学.
背景情况:
- 2019年冠状病毒病 (COVID-19) 流行病影响了全球健康,包括孕妇人口.
- 肝功能异常是严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 感染的潜在并发症.
研究的目的:
- 为了确定COVID-19后孕妇中异常肝功能测试 (LFTs) 的发生率.
- 调查与异常LFTs相关的因素及其对怀孕结果的影响.
主要方法:
- 对168名患有COVID-19晚期感染的孕妇进行了回顾性分析.
- 86名怀孕妇女的异常LFT (观察组) 与82名正常LFT (对照组) 的比较.
- 包括后勤回归在内的统计分析,以确定肝损伤的危险因素.
主要成果:
- 超过一半 (51.2%) 患有COVID-19的孕妇表现出肝酶的升高.
- 母亲年龄,妊娠周和体重指数 (BMI) 被确定为肝损伤的独立风险因素.
- 观察组显示,剖腹产,产后出血,早产和新生儿并发症的发生率显著提高.
结论:
- 在SARS-CoV-2感染后,孕妇患肝损伤的风险增加.
- 先进的孕产妇年龄,妊娠年龄和BMI与更高的肝损伤概率有关.
- 在COVID-19后怀孕晚期肝功能异常可能导致妊娠不良后果.
更多相关视频
03:19Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
Published on: June 28, 2024
05:25Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
Published on: February 28, 2025
相关概念视频
Teratogenicity
Factors Affecting Drug Response: Overview
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Overview of Carbohydrate Metabolism
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
