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Updated: Sep 19, 2025

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甲状腺激素有助于JAK/STAT通路的异常激活,促进T细胞淋巴瘤的传播

Mercedes Debernardi1, Alejandro Correa2, Lucero Alvarado1

  • 1Laboratory of Neuroimmunomodulation and Molecular Oncology, Instituto de Investigaciones Biomédicas, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Catolica Argentina, Buenos Aires, Argentina.

Blood advances
|June 9, 2025
PubMed
概括

甲状腺激素 (THs) 在T细胞淋巴瘤 (TCL) 中激活JAK/STAT信号. 向整合素αvβ3与西伦基提德和贝克萨罗表明,通过减少瘤生长和转移,TCL治疗具有前途.

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