老年人中黄醇摄入量和中风之间的关系:来自NHANES (2007-2010年和2017-2018年) 的横截面研究
Xuehua Cheng1, Ting Peng2, Li Han1
1Department of Traditional Chinese Medicine (TCM) Geriatrics, Huadong Hospital, Fudan University, Shanghai, PR China.
饮食中摄入较高的黄类素,特别是像瑞这样的黄类素,与美国老年人中风发病率较低有关. 这表明通过饮食预防中风的潜在好处.
科学领域:
- 营养流行病学 营养流行病学
- 老年医学 老年医学
- 心血管疾病研究研究
背景情况:
- 脑卒中是老年人死亡和残疾的主要原因.
- 研究诸如黄类的食因素可能有助于预防中风.
研究的目的:
- 检查美国老年人中饮食中黄酸盐摄入量与中风患病率之间的关联.
- 探索黄类子类,特别是黄类,在中风风险中的特定作用.
主要方法:
- 对国家健康和营养检查调查 (NHANES) 数据 (2007-2010,2017-2018) 的分析.
- 使用多变量后勤回归,受限立方线 (RCS),通用增量模型 (GAM),贝叶斯内核机器回归 (BKMR) 和SHAP值.
- 调整了包括年龄,贫困指数比率 (PIR),超脂血和体重指数 (BMI) 在内的共同变量.
主要成果:
- 较高的黄类和亚类 (例如,myricetin,quercetin,kaempferol) 的摄入量与中风患病率相反相关.
- 随着更高的黄醇摄入量 (Q4) 观察到中风几率下降了61%.
- 确定了非线性 (Quercetin/kaempferol的U形) 和线性 (myricetin) 关系,其中flavonol子类具有负面的联合效应.
结论:
- 饮食中增加的黄类药物摄入量,特别是像米瑞这样的黄类药物,与美国老年人中风发病率的降低有关.
- 饮食中的黄类药物摄入可能为老年人中风预防提供保护性益处,特别是那些年龄在60-70岁且收入较高的人.
更多相关视频
14:39Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
12:00Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
Published on: July 5, 2017
相关概念视频
Regulation of Stroke Volume
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Cancer Prevention
Some...
Cardiac Output and Stroke Volume
In an average resting adult male, the typical cardiac...
