导航复杂性:通过修改的Delphi研究,通过肥胖患者的营养不良诊断达成共识的挑战
Natasha Nalucha Mwala1, Jeanne J F A In 't Hulst1, Barbara S van der Meij2
1Department of Nutrition, Dietetics and Lifestyle, School of Allied Health, HAN University of Applied Sciences, Nijmegen, the Netherlands.
Clinical nutrition ESPEN
|June 9, 2025
概括
制定肥胖的营养不良定义是复杂的. 专家们就使用全球营养不良领导倡议 (GLIM) 标准达成共识,但需要解决准确诊断的体重减轻和肌肉质量等特定参数.
科学领域:
- 临床营养学 临床营养学
- 肥胖医学 肥胖医学
- 诊断标准开发 发展诊断标准
背景情况:
- 在肥胖患者中诊断营养不良存在独特的挑战,原因是生理学变化和被忽视的因素.
- 现有的全球营养不良定义不能充分解决肥胖的复杂性.
研究的目的:
- 制定一个工作定义,用于诊断营养不良,特别是在肥胖个体.
- 在专家之间就肥胖中营养不良的关键诊断参数建立共识.
主要方法:
- 从2024年3月到7月,采用了一种经过修改的三轮Delphi方法,涉及25名专家.
- 在45个初步声明上寻求共识,随后修订以全球营养不良领导倡议 (GLIM) 标准为重点.
- 协议门设置为≥70%,最终的共识通过二元同意/不同意尺度进行评估.
主要成果:
- 共识支持全球营养不良领导倡议 (GLIM) 标准作为一个基本要素.
- 体重减轻,肌肉质量和功能参数的具体门仍然没有解决.
- 关于C-反应蛋白值达成协议,尽管在肥胖的慢性炎症背景下对其解释进行了辩论. 强调了饮食质量和数量评估,以及饮食专家的意见.
结论:
- 在这项研究中,未能为肥胖中营养不良的最终工作定义.
- 进一步的研究是必不可少的,以完善和验证非自愿减肥,肌肉质量,炎症标志物和饮食摄入量的参数.
- 这项研究为未来对肥胖人口营养不良诊断的研究提供了关键的基础.
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