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Updated: Jun 13, 2025

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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在快速化学重编程的细胞命运过渡过程中解读替代拼接模式

Yunkun Lu1,2, Kainan Lin3, Yeling Ruan4

  • 1Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China. kevenloo1@zju.edu.cn.

BMC biology
|June 9, 2025
PubMed
概括

快速化学重编程 (FCR) 在细胞命运过渡过程中揭示了动态替代拼接 (AS) 模式. 外基因排斥占主导地位,Ptbp3被确定为影响表观遗传调节的关键拼接因子.

关键词:
另一个替代拼接.细胞命运过渡 细胞命运过渡一个类似于Diapause的状态.快速的化学重编程

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