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Updated: Sep 19, 2025

CRISPR Epigenome Editing in Human Cells using Plasmid DNA Transfection and mRNA Nucleofection Delivery
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通过结构交换DNA翻译器驱动的合成CRISPR网络

Luca Capelli1, Sofia Marzari1, Elena Spezzani1

  • 1Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area Delle Scienze 17/A, Parma 43124, Italy.

Journal of the American Chemical Society
|June 10, 2025
PubMed
概括

转录因子 (TFs) 现在通过工程DNA翻译器调节CRISPR-Cas12a活动. 这项创新通过创建新的蛋白质核酸通讯道, 实现了精确的控制和新的合成生物学应用.

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