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通过使用特权结构二二来设计的衍生物的毒性评估:LQFM310,一个尼菲迪平类型的类似物

Amanda C Silva1,2, Michele R Machado2, Gerlon A R Oliveira3

  • 1Laboratory of Medicinal Pharmaceutical Chemistry (LQFM), School of Pharmacy, Federal University of Goiás, Goiânia, Goiás, Brazil.

Journal of applied toxicology : JAT
|June 10, 2025
PubMed
概括

一种新型化合物,LQFM310,是通过分子杂交合成的,它结合了二二和丁氧 (BHT) 特性. 与nifedipine相比,LQFM310在斑马鱼胚胎中表现出抗氧化能力和更安全的毒理学特征.

关键词:
另一种方法是替代方法.但是基酸烯的基酸.分子混合化分子混合化.尼菲迪平因 (nifedipine) 是一种尼菲迪平因 (nifedipine) 的一种药物.反应性氧物种 (ROS) 是一种反应性氧物种.基于斑马鱼的模型

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