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Updated: Jun 13, 2025

In Vitro Three-Dimensional Sprouting Assay of Angiogenesis Using Mouse Embryonic Stem Cells for Vascular Disease Modeling and Drug Testing
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In Vitro Three-Dimensional Sprouting Assay of Angiogenesis Using Mouse Embryonic Stem Cells for Vascular Disease Modeling and Drug Testing

Published on: May 11, 2021

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通过Src抑制和Tie2激活促进血管稳定:基于模型的分析分析

Yu Zhang1, Christopher D Kontos2, Brian H Annex3

  • 1Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21215, USA.

iScience
|June 10, 2025
PubMed
概括

这项研究模拟了血管内皮生长因子 (VEGF) 和血管蛋白质 (Ang) -Tie通路,以了解血管生长和泄漏. 慢性Ang1保护VEGF诱导的泄漏,并结合Src抑制与Tie2激活可以防止泄漏而不妨碍血管生成.

关键词:
生物信息学是一种生物信息学.生物科学 生物科学自然科学 自然科学药物信息学 是一种信息学.

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