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患有言语迟缓的儿童的甲酸血水平

Nihal Yaman Artunç^1,2, Anıl Yirün^3,4, Gizem Yıldıztekin⁵

¹Izmir Democracy University, Buca Seyfi Demirsoy Training and Research Hospital, İzmir, Turkey.

Toxicology reports

|June 10, 2025

概括

环境污染物称为酸盐可能会增加儿童发言迟缓的风险. 在言语迟缓的儿童中发现了较高水平的某些甲酸盐,这表明存在潜在的联系. 需要进一步的研究.

科学领域:

环境健康环境健康
儿科发展儿科发展
毒理学毒理学毒理学

背景情况:

语音延迟是儿童常见的发育问题.
酸盐,内分泌干扰环境污染物,被怀疑是发育问题的风险因素.

研究的目的:

调查甲酸盐暴露与儿童言语迟缓之间的关联.
为了比较有和没有言语迟缓的儿童的酸盐水平.

主要方法:

一个病例对照研究,涉及50名孤立言语迟缓的儿童和40名健康的对照.
语音延迟风险因素和甲酸盐暴露源的评估.
使用高压液态染色学量化甲酸盐水平的血量化 (二乙二甲酸盐 (DEHP),单乙二甲酸盐 (MEHP) 和二乙甲酸盐 (DBP)).

主要成果:

与对照组相比,发言迟缓的儿童的MEHP和DBP的血水平显著更高 (p < 0.001).
DEHP水平在两组之间没有显著差异 (p = 0.233).
使用多重线性回归调整后的分析证实了语音延迟组的MEHP和DBP水平较高.

结论:

发言迟缓儿童的MEHP和DBP血水平升高表明,甲酸盐暴露可能是导致风险因素.
需要进一步的流行病学研究来证实甲酸盐暴露与言语延迟之间的联系.

关键词:

DBP DBP DBP 的意思是什么意思在DEHP中,DEHP是DEHP.内分泌干扰物干扰内分泌干扰物这就是 MEHP 的意义.甲酸是一种甲酸.语音延迟是一个问题.

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