手术后的外科和持续的阿片类药物使用:一个范围审查
Bader Almodibeg1,2,3, Jungwoo Kang2, Patrice Forget2,3,4,5
1Anaesthesia and Operation Technology Department, King Khalid University, College of Applied Medical Sciences, Khamis Mushait, Asir, Saudi Arabia.
BJA open
|June 10, 2025
概括
手术后持续使用阿片类药物是一个问题. 手术前使用阿片类药物预测持续使用,但手术内和短期术后的影响需要更多的研究. 长期处方增加了未来的阿片类药物风险.
科学领域:
- 疼痛医学 医学 疼痛医学
- 外科手术的结果
- 药理学 药理学是指药理学的学科.
背景情况:
- 手术后持续使用阿片类药物是一个重大的临床挑战.
- 现有的研究往往忽视了全面的外科手术期阿片类药物暴露.
- 除了先前的阿片类药物使用之外,确定可靠的预测因素至关重要.
研究的目的:
- 进行范围审查,确定有关术后期阿片类药物使用和术后持续阿片类药物使用的知识差距.
- 探索术前,术后和术后阿片类药物使用与长期阿片类药物依赖之间的关联.
- 为未来的研究方向提供信息,以减轻持续的阿片类药物使用.
主要方法:
- 全面的数据库搜索关于成年外科病人周术期使用阿片类药物和持续使用的前性研究.
- 系统审查和综合发现的发现,从确定研究.
- 分析阿片类药物暴露和持续使用的不同外科手术前阶段之间的关联.
主要成果:
- 术后期使用阿片类药物和术后持续使用阿片类药物之间存在复杂的关系.
- 手术前使用阿片类药物与持续使用相关.
- 术内和短期术后阿片类药物使用的影响尚不清楚,但3个月的处方预测6个月和12个月的持续使用.
结论:
- 需要进一步的研究来阐明在手术前的阿片类药物使用者中持续使用阿片类药物的调解因素.
- 术内和住院术后阿片类药物消费的具体作用需要研究.
- 了解短期术后阿片类药物处方 (≤30天) 对于风险评估至关重要.
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