如何定义治疗阻断性成:一个范围审查
Nicholas L Bormann1, Jesse R Burson, Emily M Burson
1Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN (NLB, JRB, VK, TSO); Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD (EMB); Mayo Clinic Libraries, Mayo Clinic, Rochester, MN (MMG); Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN (BJC); Department of Psychiatry, Washington University in St Louis, St Louis, MO (MG).
Journal of addiction medicine
|June 10, 2025
概括
在成领域,对于那些使用多种治疗而没有缓解的个体缺乏明确的定义. 使用"治疗耐药"可能更好地描述这个群体,并指导量身定制的干预措施.
科学领域:
- 成 药物 药物 药物 药物
- 临床心理学 临床心理学
- 神经科学是一个神经科学.
背景情况:
- 成领域缺乏标准化术语,用于持续使用物质的个人,尽管有多次治疗尝试.
- 这种模糊性阻碍了研究和临床努力,以识别和支持这一群体.
研究的目的:
- 进行范围审查,以评估在现有文献中如何定义持续治疗不反应成的概念.
- 确定常见的术语和用于定义这一患者群体的特征.
主要方法:
- 在2024年9月16日进行了全面的文献搜索.
- 包括专注于成年物质使用人群的研究,被描述为治疗耐药或治疗不耐药,不包括双重诊断或不参与的个人.
- 在审查了1834篇摘要和379篇全文文章后,有39篇文章符合纳入标准.
主要成果:
- "耐治疗" (n=23) 和"耐治疗" (n=11) 是最常用的术语.
- 酒精和阿片类药物使用障碍是研究最多的疾病.
- 定义的具体性各不相同,但通常包括使用的严重程度,治疗史,心理社会障碍以及消费,持续时间和治疗参与的具体门.
结论:
- 为了有效的研究和临床护理,需要对持续治疗中毒无反应的一致定义.
- 建议"耐治疗"作为首选术语,而不是"耐治疗",因为它的第一人称语言.
- 达成一致的定义将有助于识别这一处于危险的群体,并制定有针对性的干预措施.
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