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Updated: Sep 19, 2025

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro
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Published on: April 8, 2020

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超分子宿主-客组件用于可调和和模块化色素向蛋白质降解

Xuetao Chen1,2, Tingting Wu1,2, Yali Chen1,2

  • 1Jiang Su Key Laboratory of Drug Design and Optimization and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, China.

Angewandte Chemie (International ed. in English)
|June 10, 2025
PubMed
概括

我们开发了宿主-客人桥梁 lysosome-targeting 嵌合体 (HGTACs),用于可调节的蛋白质降解. 这种超分子平台提供了精确的降解控制,显示了治疗应用的前景.

关键词:
肝细胞癌是肝细胞癌.异性双功能药物是一种药物.主机客户端系统.lysosome 向化马体的目标化马体蛋白质降解 蛋白质降解

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