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Updated: Jun 12, 2025

Mimicking and Manipulating Pancreatic Acinar-to-Ductal Metaplasia in 3-dimensional Cell Culture
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Published on: February 11, 2019

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埃美林是胰腺癌中瘤性KRAS驱动的核动力学效应剂

Luis F Flores1, David L Marks2, Renzo E Vera2

  • 1Division of Oncology Research, May Clinic, Rochester, United States of America.

JCI insight
|June 10, 2025
PubMed
概括

致癌突变KRAS通过调节Emerin (EMD) 来缩小癌细胞核. 耗尽EMD会增加核大小,并减少差异化胰腺癌,揭示了PDAC致癌的一个新机制.

关键词:
癌症 癌症 癌症 癌症细胞生物学 细胞生物学在瘤学瘤学.

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