使用药物坚持原因尺度 (MAR尺度) 识别中国高血压患者不坚持药物的原因
Jingjing Pan1, Bin Hu1, Xiaorong Xue1
1Department of Pharmacy, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an, People's Republic of China.
PloS one
|June 10, 2025
概括
药物不服药影响了66.9%的中国高血压患者. 诸如年龄,教育,血压和患者的信念等因素显著影响对高血压药物的坚持.
科学领域:
- 心血管医学 心血管医学
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 高血压是全球主要的健康问题,需要持续服药才能有效管理.
- 不遵守抗高血压药物对实现血压控制和预防并发症构成重大挑战.
研究的目的:
- 确定中国高血压患者中药物不服药的患病率.
- 探索社会人口统计学和与信仰相关的因素,这些因素影响了这一群体的药物坚持.
主要方法:
- 一项涉及571名住院高血压患者的横截面研究,在中国西安.
- 使用中文版本的药物坚持原因量表 (ChMAR-Scale) 来确定不坚持的原因.
- 采用二进制物流回归来分析独立的风险因子.
主要成果:
- 观察到药物不服药的高患病率,其中66.9%的患者不服药.
- 年龄,教育水平和血压类别独立地与药物坚持有关.
- 不遵守的关键原因包括与信仰相关的问题,例如基于血压或身体状况的自我调整药物,以及对长期影响的担忧.
结论:
- 在中国高血压患者中,药物不合规性很普遍,这突出了一个关键的公共卫生问题.
- 干预措施应应对社会人口统计学因素 (年龄,教育,血压类别) 和患者的信念/自我认知,以改善坚持.
- 这些发现可以指导医疗保健提供者制定有针对性的策略,以提高高血压患者的治疗坚持.
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