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Updated: Jun 13, 2025

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基于碳醇和阿拉伯的皮肤配方改善了皮肤对印梅他辛的保留

Hiroko Otake1, Ogata Fumihiko1, Yosuke Nakazawa2

  • 1Faculty of Pharmacy, Kindai University, Higashi-Osaka, Osaka, Japan.

PloS one
|June 10, 2025
PubMed
概括

阿拉伯 (GA) 成功地为皮肤凝制造了印美他辛 (IMC) 纳米晶体,增强了皮肤的吸收和保留,而不会增加全身水平. 这为纳米晶体配方提供了一个有前途的替代添加剂.

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Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
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