探索性先进的放射疗法用于骨髓母细胞瘤和骨髓母细胞瘤-一个简短的审查
Heba Turkstani1, Afrah Alfaifi1, Sunday O Akintoye1
1Department of Oral Medicine, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Oral diseases
|June 10, 2025
概括
先进的辐射疗法对治疗质母细胞瘤 (ameloblastoma) - - 一种侵袭性瘤,当手术不是一种选择时,显得有前途. 病例报告表明瘤反应良好,副作用可控,这表明可行的替代治疗方法.
科学领域:
- 口腔和牙面部外科手术
- 辐射瘤学 辐射瘤学
- 在瘤学瘤学.
背景情况:
- 骨髓母细胞瘤是一种具有挑战性的口腔瘤,以侵略性生长和高复发率而闻名.
- 手术切除是主要的治疗方法,但对于不可手术的病例,可以考虑辅助疗法.
研究的目的:
- 审查针对乳腺母细胞瘤的先进辐射治疗方法的病例报告.
- 评估治疗结果,包括瘤反应,副作用和复发.
主要方法:
- 在PubMed,谷歌学者,Embase,科学网和Scopus的系统搜索.
- 包括螺旋式断层疗法,马刀放射手术,质子束疗法和碳离子疗法治疗乳腺母细胞瘤的研究.
- 基于瘤反应,辐射副作用和复发的患者结果的评估.
主要成果:
- 78%的病例表现出瘤回归或完全反应,没有疾病进展.
- 两例病例显示部分回归或疾病稳定.
- 大多数副作用是轻微的 (1-3级皮肤炎,粘膜炎,异口症),有两个病例出现严重的毒性.
结论:
- 先进的辐射技术提供了一个有前途的替代或辅助疗法,当手术是禁忌的乳腺母细胞瘤.
- 需要进一步的研究来验证这些发现,并建立最终的治疗方案.
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