关于巴西迪奥博洛米科斯的单中心回顾性研究:特征,管理和结果
Huda Abbag1, Alaa Al Juaid2, Ahmad Alghamdi3
1Department of Pediatric, King Abdullah Specialized Children's Hospital, Jeddah, Saudi Arabia.
Journal of infection and public health
|June 10, 2025
概括
胃肠道基球菌病 (GIB) 是一种罕见的真菌感染,经常模仿儿童的其他疾病. 早期诊断和基于沃里康纳的抗真菌疗法是有效管理GIB的关键.
科学领域:
- 菌类学 菌类学是指菌类学.
- 儿童传染病 儿童传染病
- 胃肠病学 胃肠病学
背景情况:
- 胃肠道基础菌菌病 (GIB) 是一种罕见的真菌感染,由Basidiobolus ranarum引起.
- 它主要影响热带地区的儿童,并且由于其多样化的呈现,可以被误诊.
研究的目的:
- 为了回顾性地分析儿科GIB病例.
- 确定临床特征,诊断方法和治疗结果.
主要方法:
- 对2013-2023年9例儿科GIB病例进行了回顾性分析.
- 对患者人口统计,临床症状,实验室发现,受影响部位和治疗方案的审查.
- 菌根元素的组织病理学确认.
主要成果:
- 患者的中位数年龄为5岁,77.7%出现腹部症状.
- 常见的发现包括白细胞症,乙素,以及升高的炎症标志物.
- 上升结肠是受影响最严重的部位 (44.4%);以伏利康纳为基础的治疗是有效的,其中44.4%的患者实现了完全解脱.
结论:
- 在患有腹部质量和eosinophilia的儿科患者中,GIB需要高的怀疑指数.
- 最少侵入性的诊断方法至关重要.
- 基于沃里康纳的抗真菌疗法在控制GIB方面表现出有效性.
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