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Updated: Jun 12, 2025

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
07:04

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology

Published on: May 2, 2025

248

向USP47通过破坏PD-L1的稳定性来增强肝细胞癌的免疫疗法

Yixiao Jiang1, Ze Yu2, Jie Wang3

  • 1Department of General Surgery, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang, China; Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang, China.

International immunopharmacology
|June 10, 2025
PubMed
概括

在肝细胞癌 (HCC) 中,USP47使PD-L1蛋白分离并稳定. 与P5091一起抑制USP47增强了抗PD-1疗法的疗效,改善了HCC治疗结果.

关键词:
组合疗法是一种联合疗法.消灭城市的消灭.P5091 是一个P5091在PD-L1中.美国P47 USP47

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