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Updated: Jun 12, 2025

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芯片 (Ldb1) 是Zelda的假定辅因子,在胚胎基因组激活过程中形成CBP的功能性桥梁

Charalampos Chrysovalantis Galouzis1, Yacine Kherdjemil1, Mattia Forneris1

  • 1European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69117 Heidelberg, Germany.

Molecular cell
|June 10, 2025
PubMed
概括

LIM-域结合蛋白1 (Ldb1),或Chip,对于早期胚胎基因调节至关重要. 这项研究揭示了Chip作为Zelda的辅助因子,将其连接到CBP,以控制在胚胎基因组激活期间的基因表达.

关键词:
美国中央银行 (CBP) 的CBP.辅助因子 辅助因子增强发育的增强剂.胚胎发生是胚胎发生.转录因子是一种转录因子.转录规则 转录规则 转录规则紫毒基因组激活活动

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