相关实验视频

Updated: Jun 12, 2025

Rapid Synthesis and Screening of Chemically Activated Transcription Factors with GFP-based Reporters
09:22

Rapid Synthesis and Screening of Chemically Activated Transcription Factors with GFP-based Reporters

Published on: November 26, 2013

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工程转录因子结合阵列用于基于DNA的哺乳动物细胞基因表达控制

Annalise Zouein1, Brittany Lende-Dorn2, Kate E Galloway2

  • 1Department of Chemical Engineering, Imperial College London, London, UK; Imperial College Centre for Synthetic Biology, Imperial College London, London, UK; Department of Bioengineering, Imperial College London, London, UK.

Trends in biotechnology
|June 10, 2025
PubMed
概括

研究人员使用转录因子 (TF) 识别元素 (RE) 阵列开发了DNA工具,以控制哺乳动物细胞中的基因表达. 这种方法利用克隆麻烦循环重复 (CTRL) 技术,可实现精确的细胞工程和命运确定.

关键词:
调节基因表达 调节基因表达哺乳动物细胞 哺乳动物细胞合成生物学 合成生物学转录因子的转录因子转录因子诱的诱

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