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Updated: Jul 20, 2026

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[DICER1突变原发内肉瘤:分析了五个病例]

Z J Duan1, J Feng1, J P Zhang1

  • 1Department of Pathology, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, China.

Zhonghua bing li xue za zhi = Chinese journal of pathology
|June 10, 2025
PubMed
概括

DICER1-突变原发性内肉瘤是一种新的瘤实体,在年轻患者中通常呈现为高档状细胞. 诊断依赖于DICER1的遗传变化和特定的形态特征.

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Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...