[用于估计流行病学影响的分布式学习方法开发和应用的进展]
1Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing 100191, China.
概括
分布式学习对估计流行病学效应具有前景,比元分析具有优势,特别是数据异质性和罕见结果. 需要进一步的研究来提高它的效率和处理各种数据结构.
科学领域:
- 流行病学 流行病学
- 医疗健康大数据大数据
- 机器学习 机器学习
背景情况:
- 分布式学习 (DL) 正在健康大数据研究中出现.
- 传统方法面临着多中心数据隐私和异质性的挑战.
研究的目的:
- 系统地审查流行病学影响估计的分布式学习方法.
- 为使用DL的多中心研究提供方法指导.
主要方法:
- "健康/医疗大数据"和"分布式/联合学习"的文献搜索到2023年12月.
- 包含/排除标准和数据提取框架是经过专家咨询而开发的.
- 由两个独立研究人员进行的选和数据提取.
主要成果:
- 分析了自2019年以来主要来自美国发表的29篇论文.
- 开发了22种DL方法用于物流,考克斯,松回归和GLMM,以及3个分析平台.
- 在1-3轮沟通中,DL方法显示偏差较低,在处理数据异质性和罕见结果方面表现优于元分析.
结论:
- 分布式学习是流行病学影响估计的一个有希望的方法.
- 需要进一步的研究来解决数据异质性和提高通信效率.
- 需要进一步开发DL方法,以便在多中心研究中得到强大的应用.
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