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Updated: Jun 12, 2025

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
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通过RNF20介导的H2B单双化可以保护停滞的叉子免受退化,并促进叉子重新启动

Debanjali Bhattacharya1, Harsh Kumar Dwivedi1, Ganesh Nagaraju2

  • 1Department of Biochemistry, Indian Institute of Science, Bangalore, Karnataka, 560012, India.

EMBO reports
|June 10, 2025
PubMed
概括

在复制DNA位点上,RNF20促进H2B单双化 (H2Bub). 这保护了停滞不前的复制分叉免受退化,并帮助它们重新启动,在复制压力期间保护基因组.

关键词:
叉子保护 叉子保护基因组稳定性 基因组稳定性H2B 单氧化化在RNF20中,RNF20是指RNF20的字母.复制 压力 复制 压力

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