65岁以上2型糖尿病患者的老年状况特征:evkalipt研究的亚分析
Ekaterina N Dudinskaya1,2, Natalia M Vorobyeva1, Julia S Onuchina3,4
1Russian Gerontology Research and Clinical Center, Moscow, Russia.
与没有这种情况的老年患者相比,患有2型糖尿病 (T2DM) 的老年患者表现出较差的老年状况. 在老年人中,T2DM与虚弱,疼痛和抑郁症的风险增加有关.
科学领域:
- 老年学是一门学科.
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 2型糖尿病 (T2DM) 在老年人中很普遍,但对其对老年状况的影响缺乏大规模研究.
- 了解老年T2DM患者的老年病理概况对于有针对性的干预措施至关重要.
研究的目的:
- 调查65岁及以上2型糖尿病患者老年状况的特征.
- 在老年人群中识别与T2DM相关的特定老年综合征.
主要方法:
- 一项多中心研究 (EVKALIPT) 涉及4308名65-107岁的参与者.
- 参与者被分为有T2DM (n=935) 和没有T2DM (n=3360) 的两组.
- 进行了包括调查和体检在内的综合老年病评估.
主要成果:
- 在21.8%的参与者中诊断出T2DM,主要在65-74岁年龄组.
- 二型糖尿病患者表现出更明显的老年状况变化:身体活动较低,步行速度较慢,握手强度降低 (女性),健康自我评估较差,抑郁症得分较高.
- 在T2DM患者中,慢性疼痛,虚弱,基本依赖,抑郁,尿失禁,跌倒和压力的患病率增加.
- 回归分析证实T2DM与更高的基本依赖,虚弱,压力,慢性疼痛和抑郁症的风险有关.
结论:
- 与非糖尿病患者相比,患有T2DM的老年患者表现出明显较差的老年病状.
- T2DM对身体表现产生不利影响,并增加65岁及以上人群中老年综合征的风险.
- 在T2DM患者中常规识别老年综合征对于以患者为中心的方法和改善生活质量至关重要.
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