在患有白血病脑病变的患者中,脑CT的线性高信号
Shulai Zhu1, Xinxin Pan2, Yonghong Wang3
1Department of Neurology, The Second People's Hospital of Liaocheng, The Second Hospital of Liaocheng Affiliated to Shandong First Medical University, No.306, Jiankang Street, Linqing, 252600, China.
Acta neurologica Belgica
|June 10, 2025
概括
leukemic encephalopathy 是白血病的一种罕见的神经并发症,在急性转变期间可能发生. 这一案例突显了它在急性髓性白血病中的发生,强调了提高临床意识的必要性.
科学领域:
- 血液学 血液学 血液学
- 神经学 神经学
- 在瘤学瘤学.
背景情况:
- 白血病脑病变呈现出由于白血病相关的大脑病变引起的神经和精神症状.
- 它的发病率通常很低,但在某些类型的白血病中可能会升高,如急性淋巴细胞白血病 (ALL) 和急性髓性白血病 (AML).
- 报告各不相同,有些人认为~5%的发病率,而国内数据显示<3%的AML.
研究的目的:
- 在慢性髓性白血病 (CML) 的急性转变期间呈现罕见的白血病脑病变.
- 提高对这种并发症的临床理解和识别.
- 为在CML急性转变中对白血病脑病变的有限文献做出贡献.
主要方法:
- 一位患有急性CML转变和白血病脑病变的患者的病例报告.
- 对临床表现,诊断和治疗的审查.
- 关于CML中白血病脑病变的文献综述.
主要成果:
- 该案例说明了CML急性转变期间白血病脑病变的发生.
- 观察到神经和精神疾病异常.
- 患者在我们的机构接受治疗.
结论:
- 白血病脑病变是一种不常见但显著的并发症,特别是在白血病的急性阶段或转变期间.
- 在经历急性转变的CML患者中,对神经症状需要提高警.
- 需要进一步的病例报告,以更好地定义发病率和管理策略.
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