血清25氧维生素D与儿童的血红蛋白和其他贫血参数有积极的关联:一个横截面研究
Hongli Dong1, Xiaojing Xu2, Liang Gao3
1Department of Child Healthcare and Scientific Education Section, Affiliated Maternity & Child Health Care Hospital of Nantong University, Nantong, 226018, Jiangsu, China.
Nutrition & metabolism
|June 10, 2025
概括
较高的维生素D水平 (25-氧维生素D) 与儿童更好的贫血参数有关. 这项研究表明,维生素D可能有助于预防这个年龄段的贫血.
科学领域:
- 儿科营养和健康 儿科营养和健康
- 血液学 血液学 血液学
- 内分泌学 在内分泌学.
背景情况:
- 关于25-基维生素D在儿科贫血中的作用的流行病学数据有限.
- 以前的体外研究表明,25-基维生素D与贫血调节之间存在潜在的联系.
研究的目的:
- 为了研究血清25-基维生素D水平与儿童的关键贫血参数之间的关联.
- 探索25-基维生素D与儿童群体贫血风险之间的关系.
主要方法:
- 在中国南通市对10,227名儿童进行了横截面研究.
- 测量包括血清25-基维生素D,血红蛋白,平均体质体积,平均体质血红蛋白度和血清费里丁.
- 经潜在共变量调整后的统计分析,并包括按性别分层分析.
主要成果:
- 血清25-氧维生素D与血红蛋白,平均体质体积,平均体质血红蛋白度和血清费里丁具有积极的关联.
- 较高的25-基维生素D水平与降低贫血风险显著相关.
- 高灵敏度C反应蛋白 (hsCRP) 被确定为25-氧维生素D和贫血参数之间的关系的调解者.
结论:
- 研究结果支持25-氧维生素D在中国儿童中具有抗贫血作用.
- 建议进行进一步的研究,以在不同的人群和实验环境中验证这些发现.
相关概念视频
01:25Role of Vitamins in Maintaining Bone Health
3.2K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.2K
01:23Role of Skin in Vitamin D Synthesis
5.1K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.1K
01:27Disorders of Erythrocytes
903
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
903