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Updated: Jun 12, 2025

Measuring the Kinetics of mRNA Transcription in Single Living Cells
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Measuring the Kinetics of mRNA Transcription in Single Living Cells

Published on: August 25, 2011

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diffGEK:差异性基因表达动力学

Melania Barile1,2, Shirom Chabra1, Tomoya Isobe1

  • 1Department of Haematology, Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Jeffrey Cheah Biomedical Centre, CB2 0AW, United Kingdom Cambridge.

Bioinformatics (Oxford, England)
|June 11, 2025
PubMed
概括

一种新的方法,diffGEK,通过模拟细胞分化过程中转录,剪接和降解速率的平稳变化,使得在不同条件下对基因表达动力学进行比较. 这种方法揭示了传统分析遗漏的隐藏机制差异.

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