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Updated: Jun 14, 2025

Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology
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纯能受体P2Y2活性防止了CCl4-诱导肝纤维化中的DNA损伤

Erandi Velázquez-Miranda1, Ana Patricia Juárez-Mercado1, Esperanza Mata-Martínez2

  • 1Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México.

Journal of cellular biochemistry
|June 11, 2025
PubMed
概括

这项研究揭示了P2Y2受体信号与肝纤维化中DNA双链断裂修复之间的新联系. P2Y2受体的激活会影响DNA修复,可能会影响纤维化进展和肝癌的发展.

关键词:
对DNA损伤的反应反应这就是HIF-1αl.这是一个P2Y2受体.纤维化 纤维化肝脏 肝脏 肝脏 肝脏 肝脏 肝脏γH2AXX 的时间.

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