通过认知引导的EEG神经反改善了对男性的响应抑制,这些男性患有甲基胺使用障碍
Huixing Gou1, Junjie Bu1, Yan Cheng1
1Department of Radiology, First Affiliated Hospital of USTC, and Hefei National Research Center for Physical Sciences at the Microscale and School of Life Science, Division of Life Science and Medicine, University of Science and Technology of China, Hefei (Gou, Chang Liu, Gan, Zhao, Xueli Chen, Ren, Hong, Zhang); First Department of Critical Care Medicine, Second Affiliated Hospital of Anhui Medical University, Hefei (Bu); School of Biomedical Engineering, Center for Big Data and Population Health of IHM, Anhui Medical University, Hefei (Bu); Department of Psychology, School of Humanities and Social Science, University of Science and Technology of China, Hefei (Cheng, Mengyuan Liu); Anhui Drug Rehabilitation Center, Hefei (Wang, Cao, Yu, Xiangming Chen); Center for Advanced Interdisciplinary Science and Biomedicine of the Institute of Health and Medicine (HM), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei (Zhang); Key Laboratory of Brain-Machine Intelligence for Information Behavior (Ministry of Education and Shanghai), School of Business and Management, Shanghai International Studies University, Shanghai (Zhang); Business School, Guizhou Education University, Guiyang (Zhang).
认知引导的神经反通过关闭与暗示相关的大脑活动,有效地改善了甲基胺使用障碍男性的反应抑制. 这种新的方法显示了成治疗的前景.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 成研究 研究成研究
背景情况:
- 甲基胺使用障碍 (MUD) 的特点是反应抑制受损.
- 甲基胺暗示反应性显著阻碍了MUD患者的抑制控制.
研究的目的:
- 为了研究认知引导的神经反在禁用甲基胺暗示器相关的大脑活动的有效性.
- 为了增强MUD男性的反应抑制,使用基于EEG的闭环神经反协议.
主要方法:
- 一个以认知为导向的闭环EEG神经反协议被用来训练参与者禁用与提示相关的大脑模式.
- 研究了两个MUD男性样本:一个比较真实的与约束的神经反,另一个比较真实的神经反与标准康复.
- 响应抑制被测量使用一个去/不去的任务在干预之前和之后.
主要成果:
- 与约克反和标准康复相比,真实神经反显著增强了响应抑制.
- 神经反性能与改善的响应抑制相关,这是根据基线特征可以预测的.
- 结果在第二个样本中复制,证明了干预的有效性.
结论:
- 认知引导的神经反是一种有效的干预措施,用于改善MUD的响应抑制.
- 这种神经反方法有可能在成治疗中得到更广泛的应用.
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