对于疼痛性糖尿病神经病变的手动治疗,运动和心理管理的多式干预:干预开发和可行性试验协议
David Hohenschurz-Schmidt1, Sasha Smith2,3, Annina B Schmid4
1Imperial Clinical Trials Unit, School of Public Health, Imperial College London, London, UK.
Pain management
|June 11, 2025
概括
这项研究介绍了NeuOst,这是治疗糖尿病外围神经病痛的新型多式疗法. 可行性试验将评估其可接受性和有效性,以及通常的护理.
科学领域:
- 神经学 神经学
- 疼痛管理 疼痛管理
- 临床试验 临床试验
背景情况:
- 糖尿病外围神经病变会导致严重的神经病痛,治疗选择有限.
- 身体和心理干预尚未得到充分探索,但对于多式联络疗法来说是有前途的.
研究的目的:
- 开发和测试NeuOst干预治疗疼痛性糖尿病外围神经病变的可接受性和可行性.
- 为未来的研究和干预改进提供信息.
主要方法:
- 使用MRC框架开发了NeuOst (通过自我管理和治疗来优化神经病症).
- 一个三臂随机对照试验的协议,测试NeuOst与对照和常规护理.
- 主要结果侧重于可行性指标 (招聘,保留,安全,可接受性).
主要成果:
- 该研究协议已注册 (NCT06423391).
- 将进行可行性试验,以收集有关招聘,保留和安全的数据.
- 临床和定性数据将作为二次和探索性结果收集.
结论:
- 可行性试验将为改进NeuOst干预提供必要的数据.
- 这些发现将指导后续研究这种多模式治疗糖尿病外围神经病变的方法.
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