纵向和横向肌肉硬度在膝关节骨关节炎中发生不同的变化,并且与硬度感觉不一致
Angela V Dieterich1, Katrin Skerl2, Filip Paskali3
1Ultrasound Lab, Department of Physiotherapy, Faculty of Health, Medical, and Life Sciences, Furtwangen University, Freiburg, Germany.
Frontiers in physiology
|June 11, 2025
概括
膝关节骨关节炎 (OA) 的肌肉硬性在纵向和横向平面之间有所不同. 横横刚度测量可能为管理与OA相关的肌肉变化提供临床相关性.
科学领域:
- 生物医学工程 生物医学工程
- 肌肉骨研究 研究
- 康复科学 康复科学 康复科学
背景情况:
- 膝关节关节炎 (OA) 是一种常见的疾病,引起疼痛,硬和残疾.
- 受影响个体的肌肉硬性尚不清楚,特别是其与感知症状和功能之间的关系.
- 肌肉异质性表明度可能因测量平面 (纵向与横向) 而异.
研究的目的:
- 为了研究与对照人群相比,膝关节骨质炎患者肌肉度 (纵向和横向) 的差异.
- 检查测量的肌肉度与感知到的疼痛和功能障碍之间的关系.
- 探索在不同平面上量化肌肉性的临床相关性,用于膝关节OA管理.
主要方法:
- 剪切波速率 (SWV) 用于测量胃半中和巨侧的肌肉硬度.
- 在膝关节骨质炎患者中进行了测量,并在休息和各种功能负荷条件下对照进行了匹配.
- 统计分析比较了各组之间的度,并与经过验证的结果得分 (KOOS,TSK) 相关的发现.
主要成果:
- 在承重任务期间,OA组中胃半径的纵向硬度较低.
- 横向硬度的巨大的横向硬度在休息时的OA组中更高.
- 在测量硬度和临床结果之间发现了显著的相关性,尽管感知和测量硬度没有相关性.
结论:
- 膝关节OA似乎在纵向和横向平面上不同地影响肌肉硬.
- 横向肌肉硬度测量显示了评估膝关节OA的潜在临床相关性.
- 进一步的研究可以探索针对膝关节OA特定肌肉硬性特征的治疗干预措施.
相关概念视频
01:23Knee Joint
1.6K
The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
1.6K
01:29Relaxation of Skeletal Muscles
3.1K
The period of muscle contraction primarily influences the duration of stimulation at the neuromuscular junction (NMJ), the presence of free calcium ions in the sarcoplasm, and the availability of energy or ATP to support contractions.
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open....
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open....
3.1K
01:21Skeletal Muscle Relaxants: Adverse Effects
349
Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
Unlike...
Unlike...
349
01:28Disorders of the Skeletal Muscle
913
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
913
01:28Classification of Skeletal Muscle Relaxants
2.4K
Skeletal muscle relaxants are a group of drugs that can reduce muscle stiffness and induce temporary paralysis to relieve pain. These agents can act centrally to reduce muscle tone or spasms in painful conditions such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), or spinal injuries; they are called antispasmodics or spasmolytics.
Peripherally acting skeletal muscle relaxants interfere with the neurotransmission at the neuromuscular end plate to induce paralysis during...
Peripherally acting skeletal muscle relaxants interfere with the neurotransmission at the neuromuscular end plate to induce paralysis during...
2.4K
01:29Bone Disorders
3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.4K