亲炎性巨细胞释放CXCL5,以调节T细胞功能,并限制αPD-1在肥胖症驱动的肝癌中产生的影响

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Updated: Jun 13, 2025

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation
07:46

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation

Published on: April 3, 2017

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Taojian Tu1, Handan Hong1, Diala Alhousari1

  • 1Pharmacology and Pharmaceutical Sciences, Mann School of Pharmacy, University of Southern California, 1985 Zonal Ave., Los Angeles, CA 90033, USA.

JHEP reports : innovation in hepatology
|June 11, 2025
PubMed
概括

像CXCL5这样的中性粒细胞激活化学基因 (NAC) 在肝癌进展和免疫检查点治疗耐药性方面发挥着关键作用. 向CXCL5提供了一种新的治疗策略,用于增强化驱动性肝癌的抗瘤免疫力.

关键词:
纤维化 纤维化 纤维化在HCC中,HCC是HCC.这是NAFLD/NASH.在这里,我们可以使用PTEN.

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