肌肉质量指数和高尿血症:脂肪组织作为调解器
Ya Shao1, Yu Wang1, Xuelian Jiang2
1Health Management Center, Wudangshan Branch, TaiHe Hospital, Hubei University of Medicine, Shiyan, Hubei, China.
Frontiers in endocrinology
|June 11, 2025
概括
更高的肌肉质量指数 (MQI) 与更低的高尿素血的几率有关. 脂肪组织,包括身体脂肪百分比和内脏脂肪质量,显著调解这种关系,表明公共卫生的目标.
科学领域:
- 代谢健康 代谢健康
- 肌肉骨健康 肌肉骨健康
- 公共卫生 公共卫生
背景情况:
- 肌肉质量指数 (MQI) 和高尿素血症之间的关联尚未完全理解.
- 脂肪组织在调解这种关系中的作用需要进一步研究.
研究的目的:
- 在大量成年人群中调查MQI和高尿路血症之间的关系.
- 确定脂肪组织参数 (身体脂肪百分比和内脏脂肪质量) 在MQI-高尿血症相关性中的调解作用.
主要方法:
- 利用了2011-2014年国家健康和营养检查调查 (NHANES) 中5,198名成年人的数据.
- 使用手握强度和尾骨肌肉质量 (ASM) 计算MQI.
- 采用后勤回归,通用添加模型和调解分析来评估身体脂肪百分比 (BF%) 和内脏脂肪质量 (VFM) 的关联和调解效应.
主要成果:
- 在MQI和高尿素血症 (OR:每单位增加0.50) 之间发现了显著的反向关联.
- 在MQI四分位数最高的个体中,高尿素血的几率大大降低 (OR:0.32).
- BF%和VFM分别介绍了49.32%和53.62%的协会.
结论:
- 增加肌肉质量与降低高尿路血症风险有关.
- 脂肪组织在这种关系中起着重要的调解作用.
- 针对肌肉质量和脂肪组织管理的策略可能有助于减轻高尿血和改善公共卫生.
相关概念视频
01:24Obesity
401
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
401
01:29Cholesterol: Significance and Regulation
519
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
519