菲林斯·林特斯多糖的调节作用对抗氧化能力,免疫功能,肠道功能和微生物群在受脂多糖挑战的 brojlers
Yang Li1, Shuai Wang2, Xuran Zhu2
1College of Traditional Chinese Veterinary Medicine, Hebei Agricultural University, Baoding, China.
Frontiers in microbiology
|June 11, 2025
概括
菲林斯 (Phellinus linteus) 多糖 (PLP) 补充剂改善了受脂多糖 (LPS) 挑战的 brojlers 的生长,免疫力和肠道健康. PLP增强了抗氧化能力和调节了肠道微生物群,减轻了LPS引起的损害.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
背景情况:
- 果 (Phellinus linteus) 聚糖 (PLP) 在肠道健康方面表现有前途.
- 脂聚糖化物 (LPS) 的挑战会对肉的表现和肠道完整性产生负面影响.
研究的目的:
- 调查PLP对LPS挑战下的 brojlers的影响.
- 评估PLP对生长,免疫力,肠道屏障和肠道微生物群的影响.
主要方法:
- 120个Arbor Acres肉被分为控制,LPS和PLP + LPS组.
- PLP (200 mg/kg/d) 进行注射,而LPS则在特定的日子内注射.
- 分析了生长性能,血清/十二指肠参数,基因表达,组织学和肠道微生物群.
主要成果:
- LPS挑战增长,抗氧化能力和肠道屏障功能的减少,同时增加炎症标志物.
- 补充PLP可以抵消LPS的影响,改善生长,抗氧化状态和肠道形态.
- PLP改变了肠道微生物群的组成,增加了Firmicutes/Bacteroidetes比率和有益的基因.
结论:
- 200 mg/kg的饮食PLP可提高LPS挑战型肉的生长,免疫功能和抗氧化能力.
- PLP的好处与改善肠道屏障完整性和有益的肠道微生物群调节有关.
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