对小直肠神经内分泌瘤进行内镜切除的现状
Jian-Ning Liu1, Hui Chen2, Nian Fang1,3
1Department of Gastroenterology, The Third Affiliated Hospital, Jiangxi Medical College, School of Queen Mary, Nanchang University, Nanchang 330009, Jiangxi Province, China.
World journal of gastroenterology
|June 11, 2025
概括
在查期间越来越多地检测到直肠神经内分泌瘤 (rNETs). 经过修改的内镜性粘膜下切除与粘膜下拉伸为完全切除小rNETs提供了有利的选择.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 内镜治疗药物 内镜治疗药物
背景情况:
- 直肠神经内分泌瘤 (rNETs) 是一种惰的恶性瘤,在30年内发生率增加了10倍.
- 大多数检测到的rNET都很小 (<10毫米),并在结肠镜查期间发现.
- 目前的指导方针建议进行内镜切除,但最佳方法仍在争论中.
研究的目的:
- 总结关于rNETs的内镜切除技术的证据.
- 评估不同内镜方式的疗效和安全性.
- 为临床决策提出治疗算法.
主要方法:
- 对经过修改的内镜性下切除 (mEMR) 证据的审查,并没有下伸展.
- 评估内镜下粘膜切除 (ESD) 和内镜全厚切除 (EFTR).
- 对淋巴结和远程转移的风险因素的分析.
主要成果:
- 由于rNETs的粘膜下侵袭,达到足够的切除深度至关重要.
- 带有粘膜下伸展的mEMR显示了组织学完全切除的高率.
- 这种技术也显示出有利的安全性和便利性.
结论:
- 经过修改的内镜性下切除与下伸展是对rNETs的有希望的治疗方法.
- 该技术确保了具有良好的安全性的组织学完整切除.
- 一个拟议的算法有助于对rNET管理的临床决策.
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