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手术手术中的外科手术抗凝剂:系统性审查

Alexa Clark¹, Makenna Ash¹, Paul Ghareeb²

¹Emory University School of Medicine, Atlanta, Georgia.

|June 11, 2025

概括

在手术期间继续抗血栓治疗 (抗凝固剂和抗血小板药物) 似乎比停止手术更安全. 血栓的风险超过了潜在的出血并发症,尽管需要更多的研究.

科学领域:

整形外科手术整形外科手术
心血管医学心血管医学
药理学药理学是指药理学的学科.

背景情况:

抗血栓药物 (抗凝血剂和抗血小板药物) 预防血栓栓塞事件.
指南建议在手术前3-5天停止这些疗法.
最近的证据对某些程序的这种做法提出了质疑,表明继续可能是安全和有益的.

研究的目的:

审查手和手腕手术期间继续抗凝/抗血小板治疗的文献.
评估对出血风险和血栓栓塞事件的影响.

主要方法:

对PubMed和Embase数据库进行系统审查.
包括12项相关研究在选149个结果后.
研究包括前性/后性队列和病例报告.

主要成果:

持续治疗通常不会显著增加出血并发症.
皮下血液瘤是最常见的并发症,非手术治疗.
严重的血液瘤很少见;一个病例在停止治疗后报告了肺栓塞.

结论:

在手术患者中,持续的抗血栓治疗似乎比中断更安全.
血栓塞栓事件的风险可能超过出血风险.
需要在更大的队列中进行进一步的研究.

关键词:

这是一种抗凝血药物.抗血小板药物可以抗血小板.手术手术手术手术手术经期操作性经期操作性手腕手术手术手腕手术手术

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