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Updated: May 5, 2026

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视神经中的聚胺代谢:空间代谢与AP/MALDI质谱成像的空间代谢

Sean Meehan1, Caleigh O'Connor2, Eugene Moskovets2

  • 1Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL, USA.

Methods in molecular biology (Clifton, N.J.)
|June 11, 2025
PubMed
概括

这项研究展示了用于空间多组学的矩阵辅助激光消耗/电离质谱成像 (MALDI-MSI). 它结合了代谢学和脂质学来分析小鼠视觉神经中的聚胺途径代谢物和脂质.

关键词:
AP/马尔代夫 马尔代夫 马尔代夫脂质 脂质 脂质 是一种质谱仪成像成像 质谱仪成像在OCT中嵌入的组织.眼部神经退行性疾病 眼部神经退行性疾病聚氨酸是一种多氨酸.氨基酸氨基酸是一种氨基酸.

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Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
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