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Updated: Jun 12, 2025

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mTOR通过核转位和STAT1抑制调节NLRP3炎症酶激活

Alvaro González-Dominguez1, Shuling Zhang2, Daniel Boy-Ruiz3

  • 1Division of Liver Diseases, Icahn School of Medicine at Mont Sinai, New York, New York, USA.

European journal of immunology
|June 11, 2025
PubMed
概括

猛素的哺乳动物标 (mTOR) 调节了巨细胞中的NLRP3炎症酶激活. 用拉巴胺素抑制mTOR抑制了炎症酶的活性,为相关疾病提供了潜在的治疗策略.

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