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患有克罗恩病的吸烟者面部手术结果更差:一个90天的术后分析分析
Daniel Shaham1, Shira Naveh2, Meir Zemel2
1IBD Unit, Department of Gastroenterology and Liver Diseases, Tel Aviv Sourasky Medical Center, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
American journal of surgery
|June 11, 2025
概括
当前吸烟显著增加了手术后并发症和长时间住院的风险,克罗恩氏病 (CD) 患者接受手术. 戒烟可以改善手术结果.
科学领域:
- 胃肠病学和肝病学
- 手术结果研究研究.
- 公共卫生和流行病学
背景情况:
- 吸烟是克罗恩病 (CD) 严重程度和复发的已知危险因素.
- 吸烟对CD患者外科手术前期结果的影响仍然不完全理解.
- 了解这些风险对于优化手术管理和患者康复至关重要.
研究的目的:
- 调查当前吸烟和90天的术后并发症之间的关联,克罗恩氏病患者接受腹部手术.
- 为了确定吸烟状态是否独立地预测了不良的手术结果,包括严重的并发症和长时间的停留时间.
- 为了比较当前吸烟者,过去吸烟者和从未吸烟者之间的结果.
主要方法:
- 回顾性队列研究包括294名患有CD的患者,他们在2017年至2019年期间接受了腹部手术.
- 患者被分为当前吸烟者和过去/从未吸烟者组.
- 用多变量回归分析来评估吸烟与90天术后并发症,严重并发症 (Clavien-Dindo等级≥3) 和停留时间之间的关联,并对潜在的混因素进行调整.
主要成果:
- 与过去/从未吸烟者相比,目前吸烟者 (26.8%) 的整体 (64.6%与43.7%) 和严重并发症 (19%与6.5%) 的比率显著更高.
- 吸烟与整体并发症风险增加2.17倍和严重并发症风险增加3.20倍独立相关.
- 当前吸烟者经历了显著更长的停留时间 (3.01天),过去吸烟者的结果与从未吸烟的人相似.
结论:
- 目前的吸烟是术后并发症增加和科恩病患者经历腹部手术的长时间住院的独立风险因素.
- 这些发现强调了在手术干预之前为CD患者提供戒烟干预措施的重要性.
- 优化CD患者的术后护理需要解决吸烟状况,以减轻手术风险并改善康复轨迹.
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