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在CRSwNP中FESS后的主观和客观嗅觉结果之间的差异:预测因素和临床影响
Jeong-Whun Kim1, Sung-Woo Cho1, Tae-Bin Won1
1Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea; Sensory Organ Research Institute, Seoul National University Medical Research Center, Seoul, South Korea.
Auris, nasus, larynx
|June 11, 2025
概括
预测鼻手术后的嗅觉改善是复杂的. 严重的手术前主观功能障碍强烈预测患者的感知和客观测试之间的差异,需要全面的评估,以获得更好的结果.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 鼻科 鼻科是指鼻科的专家.
- 嗅觉神经科学是一种神经科学.
背景情况:
- 长期带鼻息肉的鼻鼻炎 (CRSwNP) 通常会损害嗅觉.
- 功能性内镜外科手术 (FESS) 是为了改善CRSwNP患者的嗅觉而进行的.
- 由于主观-客观测试差异,预测嗅觉功能障碍的FESS结果具有挑战性.
研究的目的:
- 确定与FESS后主观和客观嗅觉结果之间的差异相关的术前因素.
- 改善用FESS治疗的CRSwNP患者的患者咨询和结果预测.
主要方法:
- 对接受FESS的100名CRSwNP患者 (不包括COVID-19相关的嗅觉损失) 的回顾性分析.
- 数据包括人口统计数据,鼻评分,血液中乙氨基,IgE和嗅觉测试 (布坦醇值测试[BTT],主观尺度).
- 后勤回归分析了术前的因素,预测了术后主观和客观嗅觉功能之间的差异.
主要成果:
- 手术前的BTT分数和parosmia状态预测了客观的嗅觉结果.
- 主观结局受到手术前的主观评分,氨酸细胞百分比和的影响.
- 较低的手术前主观嗅觉得分显著预测了主观和客观结果之间的差异 (OR=0.335).
结论:
- 主观和客观嗅觉结果之间的差异在CRSwNP中FESS后很常见.
- 严重的手术前主观嗅觉功能障碍是这些差异的关键预测因素.
- 组合的心理物理和主观嗅觉评估对于评估FESS结果和患者咨询至关重要.
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