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Updated: Jun 13, 2025

Isolation, Characterization, And High Throughput Extracellular Flux Analysis of Mouse Primary Renal Tubular Epithelial Cells
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Published on: June 20, 2018

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肠道微生物衍生的短链脂肪酸增强脏近壁管道细胞分泌功能

Laura Giordano1, Sabbir Ahmed1, Thomas K van der Made1

  • 1Department of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht 3584 CG, The Netherlands.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|June 11, 2025
PubMed
概括

短链脂肪酸 (SCFA),如酸盐和丁酸盐,通过增加有机离子载体-1 (OAT1) 活性来促进功能. 这增强了有害的尿性毒素的分泌,为慢性病 (CKD) 提供了潜在的营养疗法.

关键词:
在CAMP信号通道上.G-蛋白结合受体 (GPCRs) 是一种希斯脱乙酶 (HDAC) 的使用有机离子载体-1 (OAT1) 是一种有机离子载体.短链脂肪酸 (SCFA) 是一种脂肪酸.

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