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室内空气中的PCB和基阻燃剂的全球审查:对人类暴露风险的影响

Olumide Emmanuel Akinrinade¹, André Henrique Rosa¹

¹Institute of Science and Technology, São Paulo State University (UNESP), Av. Três de Março, 511, Alto da Boa Vista, 18087-180, Sorocaba, SP, Brazil.

|June 11, 2025

概括

吸入多双 (PCB) 和阻燃剂 (HFR) 是一个重要的暴露途径. 这些化学物质的室内空气度令人担忧,并且需要在人类健康风险评估中进行常规考虑.

科学领域:

环境化学环境化学
毒理学毒理学毒理学
公共卫生公共卫生

背景情况:

聚二 (PCB) 和阻燃剂 (HFR) 是具有重大环境和人类健康问题的化学物质.
虽然摄入和饮食摄入是主要的暴露途径,但证据越来越强调吸入暴露的重要性.
了解室内空气水平和吸入风险对于全面评估人类暴露至关重要.

研究的目的:

评估全球室内空气中的PCB和HFR度.
评估与吸入这些化学物质接触相关的风险.
检查室内环境中PCB和HFR的当前排放因子.

主要方法:

来自主要科学数据库 (Scopus,科学网,PubMed,谷歌学者) 的54个文档的系统文献审查.
对报告中的度,主要化学特征以及影响变异性的因素进行分析.
吸入暴露水平与其他暴露途径的比较.

主要成果:

全球检测到高度的PCB和HFR,新兴阻燃剂在土耳其达到42,000 pg/m3.
室内空气概况主要由特定的PCB和HFR同源物占主导地位,受应用和挥发的影响.
在空气形状上没有观察到显著的区域差异,但度因微环境而异.
在某些情况下,吸入暴露水平与饮食和摄入途径相似.

结论:

吸入PCB和HFR的暴露是一种关键的,经常被低估的途径,需要进行例行风险评估.
准确的被动采样率至关重要,以避免低估度.
需要制定特定的全球或区域吸入参考剂量,以进行可靠的风险评估,特别是随着挥发性化合物检测的增加.

关键词:

制阻燃剂是一种制阻燃剂.这就是HBCDDs.危险的污染物危险的污染物室内空气质量室内空气质量有机素是一种有机素.一个PBDE就是一个PBDE.斯德哥尔摩公约斯德哥尔摩公约

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