身体活动干预对晚年抑郁症状的影响:使用两个队列研究的目标试验模拟
André O Werneck1, Leandro F M Rezende2, Brendon Stubbs3
1Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom; Center for Epidemiological Research in Nutrition and Health, Department of Nutrition, School of Public Health, Universidade de São Paulo (USP), São Paulo, SP, Brazil.
Journal of affective disorders
|June 11, 2025
概括
老年人的定期体育活动显著降低了12年发展抑郁症状的风险. 这种持续的干预表明,与自然过程的进展相比,抑郁症发病率显著下降.
科学领域:
- 老年学是指老年学的学科.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 晚年抑郁症状对公共卫生构成重大挑战.
- 确定有效的干预措施来预防老年人的抑郁症至关重要.
研究的目的:
- 估计持续体育活动干预对晚年抑郁症状风险的12年影响.
- 为了比较体力活动干预下抑郁症状的发生率与老年人的自然过程.
主要方法:
- 使用来自健康和退休调查 (HRS) 和老龄化英语纵向研究 (ELSA) 的数据进行目标试验的模拟.
- 包括10,735名 (HRS) 和4,898名 (ELSA) 的老年成人参与者.
- 应用参数g公式,调整时间变化的风险因素以估计12年抑郁症状风险.
主要成果:
- 在HRS中,身体活动干预与12年抑郁症状风险降低5.20个百分点 (44.3%对39.1%).
- 在ELSA中,干预显示12年抑郁症状风险降低了8.70个百分点 (64.8%与56.1%相比).
- 这两项研究都表明,在干预期间,抑郁症发病率在统计学上显著下降.
结论:
- 长期,持续的体育活动干预与老年人抑郁症状的发病率较低有关.
- 促进定期的中度至剧烈的体力活动可能是预防老年人群抑郁症的关键策略.
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