个体肌肉缩反应受过载进展模型的影响,并与卫星细胞含量变化有关
Maíra C Scarpelli1,2, João G A Bergamasco1,2, Joshua S Godwin2
1MUSCULAB - Laboratory of Neuromuscular Adaptations to Resistance Training, Department of Physical Education, Federal University of São Carlos - UFSCar, Rod. Washington Luiz, km 235 - SP 310, São Carlos, SP, CEP 13565-905, Brazil.
个体肌肉缩对抵抗训练的反应各不相同. 增加的重复 (REPSProg) 比增加的负载 (LOADProg) 增加了更多的卫星细胞添加,但既没有影响肌核或ECM重塑生物标志物.
科学领域:
- 运动生理学 运动生理学
- 肌肉生物学 肌肉生物学
- 运动科学 运动科学 运动科学
背景情况:
- 个人对抗力训练 (RT) 的反应有很大差异.
- 了解不同超负荷进展策略对肌肉缩的影响至关重要.
- 这项研究调查了负载与重复进展对肌肉适应的影响.
研究的目的:
- 通过负荷 (LOADProg) 或重复 (REPSProg) 来比较RT的个体高反应与超负荷进展.
- 调查是否对任何协议的响应与肌核,卫星细胞,蛋白质分解和细胞外矩阵 (ECM) 重塑生物标志物的变化相关.
主要方法:
- 37名未经训练的参与者接受了为期10周的随机腿部训练 (LOADProg与REPSProg).
- 肌肉横截面积 (mCSA) 通过超声波测量训练前和训练后.
- 肌肉活检分析了肌核含量,卫星细胞,蛋白质溶解和ECM重塑标志物.
主要成果:
- 很大一部分参与者 (34%) 在REPSProg时表现出更大的缩,而19%的人对LOADProg做出了更好的反应.
- 在集群中没有观察到肌核含量,蛋白质分解或ECM重塑标记物的显著差异.
- REPSProg导致对该协议做出更好的反应的个体的卫星细胞增加.
结论:
- 超负荷进展模型影响个体肌肉缩对RT的反应.
- 通过增加重复的进展与卫星细胞的增殖有关.
- 对不同RT进展策略的反应并不能通过肌核,蛋白质分解或ECM重塑的变化来解释.
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