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Updated: Jun 15, 2025

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
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PELI2通过MAPK信号通路抑制结直肠癌的发展

Jialin Liu1, Shengyun Hu2, Liangbo Zhao3

  • 1Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450001, China.

Molecular medicine (Cambridge, Mass.)
|June 11, 2025
PubMed
概括

这项研究发现,PELI2 (E3泛素酶) 在结直肠癌中降低,抑制瘤生长和扩散. 低PELI2水平与预后不佳相关,这表明PELI2是结直肠癌的潜在治疗标.

关键词:
结肠直肠癌是一种癌症.这就是MAPKK的意思.这就是PELI2的意义.瘤发生的起源

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